PAIN MANAGEMENT SOLUTIONS

One of the most exciting areas of research in medicine involves making the most of the initial healing stages: inflammation and an increase in cells, or cell proliferation. Regenerative medicine uses your body’s natural healing resources to help regrow, repair, or replace damaged or diseased cells, organs or tissues. The four main types of regenerative therapy are prolotherapy, platelet-rich plasma (PRP), cartilage regeneration, and stem cell therapies.

Erectile Dysfunction (ED) is the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

The male sexual response cycle could be divided into its three component parts: libido (desire), erectile function, sexual activity. All kinds of factors such as psychological factors, surgery and trauma, vascular diseases, neurological factors, etc. can cause ED as long as they affect any part of the sexual response cycle. In addition, there are various implicated risk factors for SD in men such as altered lifestyle, stressful living conditions, various chronic diseases, diverse environmental pollutants and several drug side effects.

ED often involves a combination of vascular, neurological, endocrinological, and psychological factors, and so the condition is not limited to elderly men. Other risk factors such as cardiovascular disease, hypertension, diabetes, hypercholesterolemia, and smoking have been strongly associated with an increased prevalence of ED.

Normally, the blood supply to the penis originates predominantly from the internal pudendal artery, which branches into the penile artery. The penile artery then branches into the cavernous arteries. The cavernous artery enters the cavernous body and subsequently divides into many branches called the helicine arteries, which open into the cavernous sinuses. Blood in the cavernous sinuses is drained by the subtunical veins that form the venous plexuses just beneath the tunica albuginea and then returns to the circulation via 3 sets of veins; the superficial, intermediate and deep veins.

In patients with erectile dysfunction, the main issue is insufficient blood flow to the penis. Blood flow is cut off or inadequate due to insufficient opening inside the vessel to allow more blood flow due to plaque build up. This is caused by a variety of factors listed above.

1. Medications
   1. A class of agents known as type-5 phosphodiesterase (PDE5) inhibitors have become the first-line therapy for ED, as recommended by the American Urological Association (AUA) and the European Association of Urology (EAU). These include oral medications such as Phosphodiesterase-5 (PDE5) inhibitors: Sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra), and avanafil (Stendra).
   2. The 3 most commonly used medications for injection therapy are Trimix, Bimix, and papaverine. Most men begin injection therapy with Trimix, which is a mixture of 3 ingredients: alprostadil, phentolamine, and papaverine. These ingredients work by relaxing the smooth muscle and opening the blood vessels in your penis, causing an erection.  Must be stored in the refrigerator. Side effects reported were pain, priapism, bruising, and curvature or the penis.
2. Vacuum-Constriction Devices
3. Prosthetic Implants
4. Intraurethral Suppositories
5. Platelet Rich Plasma (PRP) Therapy

Erectile Dysfunction (ED) is the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

The male sexual response cycle could be divided into its three component parts: libido (desire), erectile function, sexual activity. All kinds of factors such as psychological factors, surgery and trauma, vascular diseases, neurological factors, etc. can cause ED as long as they affect any part of the sexual response cycle. In addition, there are various implicated risk factors for SD in men such as altered lifestyle, stressful living conditions, various chronic diseases, diverse environmental pollutants and several drug side effects.